thalidomide
pronunciation
How to pronounce thalidomide in British English:
UK [θəˈlɪdəmaɪd]
How to pronounce thalidomide in American English:
US [ θəˈlɪdəmaɪd]
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- Noun:
- a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis
Word Origin
- Thalidomide (n.)
- 1958, from "phthalimidoglutarimide," based on abbreviated form of naphthalene; a morning-sickness drug responsible for severe birth defects in Europe from 1956 to 1961, when it was withdrawn. It never was approved for use in America thanks to the efforts of Dr. Helen Brooke Taussig (1898-1986). Thalidomide baby is attested from 1962.
Example
- 1. Thalidomide for treatment of 24 patients with myelodysplastic syndrome .
- 2. Thalidomide combination improves response in elderly patients with multiple myeloma .
- 3. Effect of thalidomide on immune rejection after ostrich-rabbit heterolamellar corneal transplantation .
- 4. Low dose thalidomide ; hepatoma ; vascular endothelial growth factor .
- 5. Scientists have discovered the primary mechanism by which thalidomide causes malformed limbs in developing embryos .